SUBSTRATE AND OXYGEN PERSUFFLATION OF HEARTS IN STORAGE FOR TRANSPLANTATION ADAPTED INTO A RODENT MODEL
Nicola Dixon and Natalie Ferrington
HLRI WA Internal
Building on the success and insights from the SOPHiST project, our team is applying gas persufflation storage techniques to a rodent model. Such a model which has never been described in the scientific literature will enable our researchers to rapidly test adjuncts to standard gas persufflation.
Examples include adding anaesthetic agents and messenger gases such as nitric oxide into the gas stream. Those interventions that are found to be beneficial in this test system will be fast tracked into more complex models aiming for eventual human translation.
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